One of my tricks for working from home is to have a uniform and change into it when your workday starts and out of it when it ends. This small idea helps me to signal both to myself and other people around me that I am playing a different role at the moment.
I work on the computer most of the day but I also paint and often sketch and one of the joys of working from home is in the fact that I can interlace these activities in many different ways. So my work uniform is usually my painting uniform. I sketched about my work pants before but today I am saying goodbye to my work shirt - by sketching it.